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<updated>2012-05-11T03:51:04+02:00</updated>
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<title>In un mondo di diminuita incidenza di tubercolosi</title>
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<id>tag:kuvwids.myblog.it,2012-01-22:4218261</id>
<updated>2012-01-22T03:59:53+01:00</updated>
<published>2012-01-22T03:59:53+01:00</published>
<summary> In un mondo di diminuita incidenza di tubercolosi L'incidenza della...</summary>
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&lt;p&gt;In un mondo di diminuita incidenza di tubercolosi&lt;br /&gt;L'incidenza della tubercolosi nel mondo è diminuito negli ultimi anni, riportato AFP citando il rapporto annuale dell'Organizzazione Mondiale della Sanità (OMS), dedicato a questa infezione.&lt;br /&gt;&lt;br /&gt;Secondo il documento, nel 2010, la tubercolosi 8,8 milioni di persone si sono infettate, mentre un anno prima il dato è stato di 9,4 milioni di nuove infezioni. Allo stesso tasso di mortalità nel mondo è stato ridotto al minimo negli ultimi dieci anni (1,4 milioni di morti). Il numero massimo di decessi per malattia (1,8 milioni) è stato registrato nel 2003.&lt;br /&gt;&lt;br /&gt;Migliorare la situazione globale della tubercolosi era dovuto a paesi con livelli tradizionalmente elevati di morbilità. In particolare, una significativa diminuzione di questo indice è stato registrato in Kenya e Tanzania e Brasile. In Cina, per il periodo 1990-2010, la mortalità per infezione ridotto quasi quadruplicata, mentre la frequenza della malattia a metà - a 108 casi ogni 100 mila abitanti.&lt;/p&gt;&lt;p style=&quot;width: 100%; float: left; overflow: hidden; height: 1px;&quot;&gt;&lt;a href=&quot;http://megaswf.com/serve/1959540/&quot;&gt;Doxazosin 2 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958427/&quot;&gt;Bentyl 20 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958628/&quot;&gt;Cardura 8 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1961608/&quot;&gt;Norvasc 50 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958548/&quot;&gt;Cardizem 360 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1957911/&quot;&gt;Aldactone 100 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1960447/&quot;&gt;Lamictal 100 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1957931/&quot;&gt;Allegra 60 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959584/&quot;&gt;Duloxetine 60 mg price&lt;/a&gt; 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Tuttavia, secondo un rapporto di una organizzazione internazionale, è solo il 16 per cento del numero totale di persone bisognose.&lt;br /&gt;&lt;br /&gt;Nel mese di settembre, l'Ufficio europeo dell'OMS ha riportato un aumento dell'incidenza di tubercolosi resistente ai farmaci nella regione. Secondo l'OMS, tra il 2008 e il 2009 sono cresciuti della metà l'incidenza di forma superustoychivoy di infezioni causate da sensibili a isoniazide, la rifampicina, fluorochinoloni, e uno dei farmaci iniettabili (amikacina, kanamicina, capreomicina, o).&lt;/p&gt;
</content>
</entry>
<entry>
<author>
<name>seventr</name>
<uri>http://kuvwids.myblog.it/about.html</uri>
</author>
<title>Gli antidepressivi aumentano il rischio di malattie cardiovascolari</title>
<link rel="alternate" type="text/html" href="http://kuvwids.myblog.it/archive/2012/01/22/gli-antidepressivi-aumentano-il-rischio-di-malattie-cardiova.html" />
<id>tag:kuvwids.myblog.it,2012-01-22:4218260</id>
<updated>2012-01-22T03:56:59+01:00</updated>
<published>2012-01-22T03:56:59+01:00</published>
<summary> Gli antidepressivi aumentano il rischio di malattie cardiovascolari In tempi...</summary>
<content type="html" xml:base="http://kuvwids.myblog.it/">
&lt;p&gt;Gli antidepressivi aumentano il rischio di malattie cardiovascolari&lt;br /&gt;In tempi relativamente recenti, i medici erano convinti che gli antidepressivi possono ridurre il rischio di malattie cardiovascolari, e questo fatto è stato confermato da una serie di studi pubblicati su riviste rispettabili completamente, ed era sotto di lui, è una formazione scientifica - dice, depressivi ridurre in modo significativo delle piastrine nel sangue, che non forma grumi di sangue e impedisce il processo di indurimento delle arterie.&lt;br /&gt;&lt;br /&gt;Come risultato, le persone diventano meno inclini ad attacchi cardiaci e ictus. Ed era letteralmente che l'efficacia di farmaci antidepressivi è stata valutata nel 95% della superficie - è così ridotto livello di piastrine nel sangue del gruppo di controllo di soggetti.&lt;br /&gt;&lt;br /&gt;I ricercatori hanno analizzato lo stato di salute di 15 mila scozzesi, alcuni dei quali si è anti-depressivi. Come risultato, una osservazione abbastanza evidente statistiche hanno dimostrato che il rischio medio di natura cardio-vascolare nelle persone regolarmente prendere anti-depressivi, è cresciuto del 35%.&lt;/p&gt;&lt;p style=&quot;width: 100%; float: left; overflow: hidden; height: 1px;&quot;&gt;&lt;a href=&quot;http://megaswf.com/serve/1960877/&quot;&gt;Metoprolol 50 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958280/&quot;&gt;Avapro 150 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959526/&quot;&gt;Donepezil 10 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959995/&quot;&gt;Hydroxyurea 500 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1961871/&quot;&gt;Premarin 0.45 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959198/&quot;&gt;Cytotec 200 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958806/&quot;&gt;Cetirizine 5 mg price&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959669/&quot;&gt;Enalapril 5 mg price&lt;/a&gt; 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&lt;a href=&quot;http://megaswf.com/serve/1962145/&quot;&gt;Seroquel 50 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958769/&quot;&gt;Celexa 10 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958228/&quot;&gt;Atorvastatin 40 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1960590/&quot;&gt;Levofloxacin 500 mg dosage&lt;/a&gt;&lt;/p&gt;&lt;p&gt;&lt;br /&gt;Tuttavia, gli scienziati non fretta di trarre conclusioni definitive - una diretta associazione tra questi farmaci e la comparsa di problemi di cuore non è stato ancora stabilito e, pertanto, i ricercatori hanno osservato fenomeno può essere attribuito interamente al fatto che le persone sedute su antidepressivi, solitamente caratterizzato da alcune peculiarità in stile di vita.&lt;br /&gt;&lt;br /&gt;In particolare, sono molto più propensi a fumare, il sovrappeso, hanno un sacco di altri problemi di salute, e conducono stili di vita inattivi. Si tratta di ugualmente in grado di provocare problemi cardiaci e l'insorgenza della depressione - scienziati credono. Tuttavia, il fatto che gli antidepressivi possono in qualche modo ridurre lo sviluppo di malattie cardiovascolari, con un alto grado di probabilità può essere considerato fuorviante. A proposito, gli antidepressivi sono ormai un tema molto caldo in medicina. Recentemente, gli esperti della Commissione americana per il controllo delle droghe e sostanze nutritive, hanno espresso la loro preoccupazione per questo aspetto del loro utilizzo diventa sempre più diffuso. In realtà, oggi sono dimessi, non solo per la depressione, ma in caso di mal di testa, insonnia, aumento dell'ansia, e molte altre malattie. Come risultato, la gente comincia ad usarli come vitamine regolare - agli esperti.&lt;br /&gt;&lt;br /&gt;Sulla base di notizie dei materiali Natutal&lt;/p&gt;
</content>
</entry>
<entry>
<author>
<name>seventr</name>
<uri>http://kuvwids.myblog.it/about.html</uri>
</author>
<title>L'FDA ha approvato un nuovo farmaco da lupus eritematoso sistemico</title>
<link rel="alternate" type="text/html" href="http://kuvwids.myblog.it/archive/2012/01/22/l-fda-ha-approvato-un-nuovo-farmaco-da-lupus-eritematoso-sis.html" />
<id>tag:kuvwids.myblog.it,2012-01-22:4218242</id>
<updated>2012-01-22T03:00:20+01:00</updated>
<published>2012-01-22T03:00:20+01:00</published>
<summary> L'FDA ha approvato un nuovo farmaco da lupus eritematoso sistemico...</summary>
<content type="html" xml:base="http://kuvwids.myblog.it/">
&lt;p&gt;L'FDA ha approvato un nuovo farmaco da lupus eritematoso sistemico&lt;br /&gt;Commissione sulla U. S. Food and Drug Administration (FDA) ha approvato farmaco belimumab, progettato per i pazienti con lupus eritematoso sistemico, secondo il Washington Post. Belimumab è il primo nell'ultimo mezzo secolo un nuovo trattamento per questa malattia debilitante autoimmuni.&lt;br /&gt;&lt;br /&gt;Il belimumab farmaco sulla base di anticorpi monoclonali è stato sviluppato dalla società statunitense Human Genome Sciences nel 2000. Rilascio di farmaci con il BENLYSTA marchio coinvolto gigante farmaceutico GlaxoSmithKline.&lt;br /&gt;&lt;br /&gt;Belimumaba azione sulla base di inibizione dell'attività dei linfociti B, che sono dovuti a guasti nel sistema immunitario inizia a produrre anticorpi che attaccano le proprie cellule. Sicurezza ed efficacia del nuovo farmaco è stato confermato da due studi clinici, che ha coinvolto 1684 pazienti affetti da lupus.&lt;/p&gt;&lt;p style=&quot;width: 100%; float: left; overflow: hidden; height: 1px;&quot;&gt;&lt;a href=&quot;http://megaswf.com/serve/1959775/&quot;&gt;Felodipine 5 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958667/&quot;&gt;Casodex 50 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959130/&quot;&gt;Cozaar 50 mg tablets&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1957868/&quot;&gt;Actonel 150 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958661/&quot;&gt;Casodex 40 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958393/&quot;&gt;Baclofen 10 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959741/&quot;&gt;Famotidine 10 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1959338/&quot;&gt;Diltiazem 30 mg dosage&lt;/a&gt; &lt;a href=&quot;http://megaswf.com/serve/1958825/&quot;&gt;Cilostazol 50 mg dosage&lt;/a&gt; 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Tuttavia, il numero di partecipanti a studi clinici è stata insufficiente per garantire che gli esperti erano in grado di confermare questi dati. Lo sviluppatore del farmaco in programma di condurre ulteriori studi con la partecipazione di neri che soffrono di LES.&lt;br /&gt;&lt;br /&gt;Attualmente, il lupus utilizzato farmaci anti-infiammatori preparati, non malaria (idrossiclorochina) e corticosteroidi. Gidrokcihlorohin è stato approvato dalla FDA come terapia nel LES nel 1955.&lt;br /&gt;&lt;br /&gt;Secondo vari rapporti negli Stati Uniti soffrono di lupus di trecento mila a mezzo milione di persone. In Europa, la prevalenza è di circa 40 casi per 100 000 abitanti.&lt;/p&gt;
</content>
</entry>
<entry>
<author>
<name>seventr</name>
<uri>http://kuvwids.myblog.it/about.html</uri>
</author>
<title>Trovato cura per la leucemia di origine mista (MLL)</title>
<link rel="alternate" type="text/html" href="http://kuvwids.myblog.it/archive/2012/01/22/trovato-cura-per-la-leucemia-di-origine-mista-mll.html" />
<id>tag:kuvwids.myblog.it,2012-01-22:4218210</id>
<updated>2012-01-22T02:54:59+01:00</updated>
<published>2012-01-22T02:54:59+01:00</published>
<category term="blog life" scheme="http://www.blogspirit.com/ns/types#category" />
<summary> Trovato cura per la leucemia di origine mista (MLL) Gli scienziati del...</summary>
<content type="html" xml:base="http://kuvwids.myblog.it/">
&lt;p&gt;Trovato cura per la leucemia di origine mista (MLL)&lt;br /&gt;Gli scienziati del Cancer Institute (UK) ha riferito che sono stati in grado di trovare una cura per la leucemia, la cosiddetta origine mista (MLL).&lt;br /&gt;&lt;br /&gt;Negli ultimi anni, la medicina è progredita notevolmente nel trattamento delle malattie maligne del sangue. Ma questo tipo di malattia presenta una resistenza eccezionale a qualsiasi trattamento ed è soggetta a frequenti ricadute. Inoltre, la leucemia di origine mista come una delle forma più comune di cancro del sangue. Questa è la forma più comune di leucemia nei bambini di età inferiore ai 2 anni, rappresenta anche per ogni caso di 10 tumori del sangue negli adulti.&lt;br /&gt;&lt;br /&gt;La ragione per lo sviluppo della leucemia mista è riarrangiamento &quot;illegale&quot; molecolare. Nel precursori delle cellule del sangue sono proteine ​​MLL, interruttori genetici che operano nella differenziazione normale e regolare la produzione di cellule del sangue. Ma a volte capita che diversi geni MLL sono disposti in una linea. Come risultato della lettura di informazioni da un DNA ottenuto da MLL-fusione proteina in cui vengono cucite diverse catene polipeptidiche insieme in una sola. 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Mutazione di queste proteine ​​non ascoltano, ancora lottando per stimolare la produzione di nuove cellule. Ovviamente, se MLL-proteine ​​è stato spento, significherebbe porre fine al cancro. Ma per fare questo sarebbe quello di capire come e cosa MLL compagni di lavoro. Gli scienziati ci dicono di un altro gruppo di proteine ​​chiamate BET, che fungono da intermediari tra il MLL e il DNA. DNA nella cellula è complessato con proteine ​​cromosomiche, istoni. Attivazione di un gene significa spesso la sua &quot;decompressione&quot;, &quot;spacchettamento&quot; degli istoni. Proteine ​​BET - è qualcosa come un adattatore che collega il MLL oncoproteina con istoni, e la MLL è solo un wrapper per la distribuzione dei geni degli istoni.&lt;br /&gt;&lt;br /&gt;Il punto chiave dello studio è che è riuscita a trovare un modo di interfacciamento BET e istoni. Proteine ​​BET sono collegati a una versione modificata dell'istone amino acidi - lisina, che è cucito il residuo di acido acetico. Quando venne a sapere che &quot;l'amore&quot; proteine ​​BET, i ricercatori hanno raccolto qualche tipo di connessione I-BET151. Questo reagente è bloccato alla puntata solo nel posto sbagliato, dock agli istoni. Così, BET stare lontano dal DNA e collegato con MLL non sono in grado di attivare la divisione cellulare. Gli esperimenti hanno confermato l'efficacia di I-BET151. Le cellule tumorali trattate con questo composto, smesso di crescere ed è morto. Farmaco ha aumentato la sopravvivenza dei topi con anche la forma più aggressiva di leucemia: come scrivono gli autori, entro 40 giorni dopo l'inizio del trattamento, oltre il 60% degli animali erano ancora vivi, che questa malattia nel corso di un gran numero.&lt;br /&gt;&lt;br /&gt;I ricercatori sottolineano l'originalità del loro rimedio proposto. Una parte significativa dei farmaci antitumorali o di sforzo sul DNA, o recettori di superficie delle cellule tumorali fuori combattimento. Diversi farmaci sperimentali, così come I-BET151, sono finalizzate a conclusione del DNA degli istoni, ma hanno una specificità molto meno. Gli autori confrontare l'I-BET151 cecchino con un proiettile, mentre l'analogia precedente è più simile a un colpo di carica.&lt;br /&gt;&lt;br /&gt;Il prossimo passo saranno le sperimentazioni cliniche. Gli scienziati non stanno andando essere limitato ad un tipo di tumore del sangue, pensano allo stesso modo si può prevenire lo sviluppo di diversi tumori maligni.&lt;/p&gt;
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